Is there any research method that could be used in place of animal experimentation?

Medical research is currently progressing on a non-vegan path. Although it’s a widespread opinion that objectives are attained and benefits are eventually gained by humanity, this is surely done at the expense of animal life. Statistical evidence strongly suggests, moreover, that the research method is extremely inefficient (quoting an extract from the source):

In 2004, the FDA estimated that 92 percent of drugs that pass
preclinical tests, including “pivotal” animal tests, fail to proceed
to the market. More recent analysis suggests that, despite efforts to
improve the predictability of animal testing, the failure rate has
actually increased and is now closer to 96 percent.

Reading above gives only half of the insight. What is not possible to tell is how many drugs would have been effective on humans but were stopped by the currently adopted metric of “not tested successfully on animal subjects”

It is clear that there is a need to find better techniques to progress in the field. By better I mean more targeted to humans, more efficient and less expensive. And of course I would like to restrain the field to techniques which are ethically acceptable from a vegan point of view.

Are there any promising techniques that could someday be used for research in place of animal experimentation?

Are there any animal behaviors that can be used to predict weather conditions within a 24 hr time period?

There are many folklore tales of animals being used to predict weather. Just a few examples from the Old Farmers Almanac:

  • When cats sneeze, it is a sign of rain.

  • If the mole digs its hole 2½ feet deep, expect severe weather; if two
    feet deep, not so severe; if one foot deep, a mild winter.

  • Bats flying late in the evening indicates fair weather.

I have not been able to find much evidence to back these tales that I have come across. However, although not necessarily a prediction, the relationship of a cricket’s chirp to temperature does seem to show how in tune animals can be with weather conditions. In fact, this relationship is also known as Dolbear’s law, named after the American physicist Amos Dolbear, who published an article on the subject called The Cricket as a Thermometer. It is expressed as:

Tf=50+(N60-40/4)

where Tf is degrees in Fahrenheit
and N60 is chirps per minute

It is generally believed that Dolbear observed the snowy tree cricket to come up with his equation. The formula is believed to be accurate to within a degree or so for the field cricket. Generally speaking, the relationship is believed to hold true because as temperature rises, the cold blooded cricket’s metabolism will also rise, providing more energy for muscle contractions and thus for chirping.

Are there observable behaviors to look for in animals that can be a harbinger of changing weather conditions? For example, say you are on a 2-3 day hike with no way to access weather forecasts and somehow you forgot to check the forecast before leaving.

Is there an official list of Fabuland animal characters?

I found in an old box these animal characters.

They are all LEGO original (the logo is present on all their parts).

They are 25, maybe 30, years old. I think is the Fabuland series. I wonder if there is any way to discover how many they were and if there is any way to complete the collection.

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